POST – What are ACEI and ARB Medications?

After my last post, I have had a number of requests for “what is an ACEI and ARB”.  This post is meant to provide a slightly more detailed explanation of these medications.

  • ACEI = Angiotensin Converting Enzyme Inhibitor
  • ARB = Angiotensin 2 Receptor Blockers

 

  • These meds have been used for hypertension for a number of decades, and have proven to be very effective in controlling blood pressure.
  • As a result of the underlying “mechanism of action” (MOA) of these meds, the quantity of ACE2 receptors are increased, specifically in the lungs.
  • Since there is a new theory that Covid-19 is “entering” the lung cells thru the ACE2 receptor, an increase in such receptors “may” increase your likelihood of getting the illness.

 

NOTE:  As of the date of this post, this is ONLY a theory, and not yet proven.  Since it is quite easy to switch to a different medication for BP control, we should all at least consider making this switch during this pandemic.

 


 

The following is a list of ACEI and ARB medications available in the US.

  • ACE Inhibitors
    • benazepril (Lotensin)
    • captopril (Capoten- discontinued brand)
    • enalapril (Vasotec, Epaned, [Lexxel- discontinued brand])
    • fosinopril (Monopril- Discontinued brand)
    • lisinopril (Prinivil, Zestril, Qbrelis)
    • moexipril (Univasc- Discontinued brand)
    • perindopril (Aceon)
    • quinapril (Accupril)
    • ramipril (Altace)
    • trandolapril (Mavik)

 

  • ARBs
    • azilsartan (Edarbi)
    • candesartan (Atacand)
    • eprosartan (Teveten)
    • irbesartan (Avapro)
    • telmisartan (Micardis)
    • valsartan (Diovan)
    • losartan (Cozaar)
    • olmesartan (Benicar)

 

Stay safe !

  • Sudhir S. Athni, MD
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